1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity associated with bortezomib, a proteasome inhibitor used in the remedy of several myeloma. Its synthesis or study is essential for guaranteeing the purity and basic safety with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor in the synthesis of abiraterone acetate, a drug Utilized in the cure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A crucial compound in the synthesis of imatinib, a drug that targets precise sorts of cancer, together with Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers like breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their review is vital for optimizing the production approach and making sure higher purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is used to treat breast cancer, and these intermediates are involved with its production.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the therapy of breast cancer. Several intermediates assist in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug productive in treating cancers like ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan 17b)-7-[9-[(4 Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug used in the remedy of colorectal cancer and smaller mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved with the synthesis of adamantane derivatives, that have many apps, including antiviral properties.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for kind 2 diabetic issues that inhibits the enzyme DPP-four to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is associated with the synthesis of various gluconic acid derivatives, which can be used in foods, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor in the synthesis b-D-Ribofuranose of canagliflozin, a medication used to manage form two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).